November 14, 2008

John Muir (1838 to 1914) and advice for surviving the Economic Crisis of 2008

John Muir was one of the first climbers to explore and climb many of the peaks in Yosemite Valley in California’s High Sierra. During his first ascent of Mount Ritter in 1872, he became gripped with fear.

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November 14, 2008

Beauty and the Beast?

Several large Pharma companies have announced interest in acquiring small biotech companies. Many Pharma companies have reduced or eliminated drug discovery efforts, and with stock prices back at 2003 levels, there certainly is a great deal of sense in these acquisitions. But finding another way to integrate these companies and their development portfolio also makes a great deal of sense.

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November 7, 2008

Kerfuffle! (pt 1)

\k?r-’f?-f?l\ to become disheveled. A kerfuffle is the polite term for a cascading series of errors that can be initiated by a seemingly innocuous event that then leads to other errors that gain in severity and impact. This essay describes a strategy for eradicating or minimizing the impact of kerfuffles in pharmacometrics.

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